Download E-books Treatment of Cystic Fibrosis and Other Rare Lung Diseases (Milestones in Drug Therapy) PDF

By Arata Azuma, Michael S. Schechter

This quantity describes the pathogenesis and pathophysiology of numerous pulmonary illnesses in addition to their therapy. It additionally discusses the underlying genetic and molecular organic foundation, which opens the best way for brand new remedies for those conditions.

It makes a speciality of the therapy of cystic fibrosis together with CFTR (cystic fibrosis transmembrane-conductance regulator) modulator remedies, drug treatments that increase airway floor liquid in addition to anti inflammatory and anti-infective treatments. additional subject matters comprise long term, low-dose macrolide remedy for diffuse panbronchiolitis; novel brokers for formerly untreatable idiopathic pulmonary fibrosis; attainable new remedies for pulmonary alveolar proteinosis (PAP); and a number of novel healing objectives for treating lymphangiomyomatosis. study into those stipulations has ended in significant advances in our figuring out of the underlying genetic and molecular foundation of this affliction, and to dramatic advancements in survival and caliber of lifestyles for affected individuals.

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